✅ Product Benefits & Highlights

• Improves microcirculation and tissue oxygenation by reducing blood viscosity and enhancing red blood cell deformability—ideal for peripheral arterial occlusive disease, leg ulcers, gangrene, cerebral vascular insufficiency, and retinal circulatory disturbances 

• Controlled-release formulation: 400 mg CR tablets taken 2–3 times daily with meals; recommended therapy duration is at least 8 weeks, monitor effects over 2–4 weeks 

• Affordable and highly available: Priced around ৳7.04 per tablet (~৳70 per 10-count strip); manufactured by Square Pharmaceuticals and distributed widely in Bangladesh 

⚠️ Safety, Interactions & Precautions

• Common side effects: nausea, vomiting, headache, dizziness, flushing, abdominal discomfort, diarrhea, pruritus, rash, angina, arrhythmias, hypotension 

• Serious but rare risks: thrombocytopenia, leucopenia/neutropenia, angioedema, cholestasis, aseptic meningitis, psychiatric symptoms, hemorrhage 

• Drug interactions:

  • May potentiate hypoglycemic effect of insulin or oral antidiabetics—monitor blood sugar.

  • Increases anticoagulant activity with warfarin or vitamin‑K antagonists—monitor INR.

  • Enhances hypotensive effect of antihypertensives.

  • May raise theophylline levels, increasing risk of toxicity.

  • Ciprofloxacin and cimetidine can raise pentoxifylline levels—increased adverse reactions.

  • Additive bleeding risk when combined with platelet aggregation inhibitors or NSAIDs (excluding selective COX‑2 inhibitors) 

• Contraindications: hypersensitivity to pentoxifylline or methylxanthines; active major bleeding; recent cerebral or retinal hemorrhage 

• Use in special populations:

  • Renal impairment (CrCl <30 mL/min): reduce dose by 30–50%.

  • Hepatic impairment: use lower starting dose.

  • Elderly or hypotensive patients: start low, titrate gradually.

  • Pregnancy & lactation: Category C—avoid unless necessary; excreted in breast milk 

🧠 Why This SEO Strategy Works

• Targets both brand and generic terms: “Oxifyl CR” and “Pentoxifylline CR” increase search visibility.

• Focuses on peripheral vascular disease and circulatory outcome keywords—major search queries in cardiovascular health.

• Emphasizes local context with pricing, manufacturer (Square Pharmaceuticals), and Bangladesh availability.

• Includes safety, interaction, and dosing keywords commonly searched by patients and healthcare professionals.