✅ Product Benefits & Highlights

• Methotrexate rescue therapy: Neutralizes acute toxicity from folic acid antagonists like methotrexate and trimethoprim—critical in oncology and immunosuppressive treatment protocols 

• Treats folate deficiency anemia: Indicated for megaloblastic anemia due to nutritional deficiency, pregnancy, infancy, malabsorption, liver disease, or sprue 

• Active folate form: Folinic acid bypasses dihydrofolate reductase, providing immediate folate replenishment even when folic acid is ineffective or blocked 

• Convenient dosing:

  • Toxicity rescue: typically 15 mg every 6 hours for 2–3 days

  • Folate deficiency: 5–15 mg once daily, depending on clinical need and prescription 

• Local pricing: Approximately ৳9 per tablet (~৳90 per 10‑tablet strip); manufactured by Square Pharmaceuticals and commonly stocked across Bangladesh 

⚠️ Safety, Interactions & Precautions

• Possible side effects: Mucositis, stomatitis, leukopenia, diarrhea; allergic reactions such as rash, urticaria, or even rare anaphylaxis 

• Contraindications: Known hypersensitivity to calcium folinate; avoid in pernicious anemia or B₁₂ deficiency (without addressing B₁₂) 

• Drug interactions: High-dose folinates may reduce efficacy of phenobarbital, phenytoin, or primidone—seizure risk in susceptible individuals; caution with fluoropyrimidines (e.g. 5‑FU) due to potential syncope/seizures 

• Pregnancy & lactation: Limited human data—should be used only if benefits justify risks; excretion in breast milk unknown 

🧠 Why This SEO Strategy Works

• Captures both brand (“Folita”) and generic (“folinic acid”) searches for broader visibility.

• Targets specific therapeutic uses—methotrexate toxicity rescue and folate-deficiency anemia—that align with user intent.

• Emphasizes local pricing, Bangladesh availability, and Square Pharmaceuticals relevance.

• Incorporates side effects, dosage, interactions, and contraindications keywords to meet information-seeking search behavior and enhance trust.