Product Benefits

Linera 5mg Tablet (Linagliptin) works as a DPP-4 inhibitor to offer several important benefits for adults with Type 2 Diabetes:⁶

• Improved Glycemic Control: It effectively lowers and maintains blood glucose levels, helping to reduce ⁷$\text{A}1\text{C}$ (a measure of average blood sugar over two to three months) when used alongside diet and exercise.⁸

• Glucose-Dependent Action: Linagliptin works by blocking the DPP-4 enzyme, which increases the levels of natural incretin hormones (GLP-1 and GIP).⁹ These hormones only stimulate the release of insulin and suppress glucagon when blood sugar levels are high, leading to a lower risk of hypoglycemia (low blood sugar) compared to some older medications (when used alone).

• Simplified Dosing: It is administered as a single 5mg tablet once daily, which simplifies the treatment regimen and helps with patient adherence.¹⁰

• No Dose Adjustment Needed in Renal Impairment: A significant benefit of Linagliptin is that no dose adjustment is typically required for patients with any degree of kidney (renal) impairment, making it a suitable option for many individuals with diabetes who also have kidney issues.¹¹

• Effective in Combination Therapy: It can be used alone (monotherapy) or in combination with other common diabetes medications, such as Metformin or Sulfonylureas, to achieve optimal blood sugar targets.