✅ Product Benefits & Highlights

• ARNi combination therapy: Combines Sacubitril (neprilysin inhibitor) and Valsartan (ARB) for enhanced efficacy in reducing mortality and hospitalizations in heart failure patients with reduced ejection fraction .

• Pediatric and adult use: Approved for adults and children aged ≥1 year with symptomatic systolic heart failure

• Flexible and dose-titrated regimen: Typical starting dose is 49/51 mg twice daily. For Valmor 50 (24/26 mg), usual initiation in ACEi/ARB-naïve or renal/hepatic impaired patients; titrate after 2–4 weeks to target dose 97/103 mg twice daily as tolerated 

• Well-tolerated: Side effects include hypotension (~18%), hyperkalemia (~12%), cough, dizziness, orthostasis; watch for rare angioedema (~0.5%) 

• Affordable availability: Priced around ৳4.50–4.80 per tablet (৳45–48 per strip of 10), widely sold across Bangladesh medical outlets 

⚠️ Safety, Precautions & Drug Interactions

• Contraindications: Avoid in patients with history of angioedema related to ACE inhibitors or ARBs; do not overlap with ACE inhibitors within 36 hours; avoid use with Aliskiren in diabetics .

• Monitor electrolytes and renal function: Recommended in individuals with diabetes, renal impairment (eGFR<30 mL/min), liver dysfunction, high-potassium diet, or hypoaldosteronism; may require dose adjustment 

• Drug interactions: Concomitant use with aldosterone antagonists, NSAIDs, lithium may increase risks of hyperkalemia or renal impairment; monitor closely and adjust as needed .

• Pregnancy caution: Contraindicated in pregnancy—especially 2nd/3rd trimester due to fetal harm risk; not recommended in breastfeeding without medical supervision 

🧠 Why This SEO Strategy Works

• Covers brand and generic terms (“Valmor”, “Sacubitril + Valsartan”) to enhance search visibility.

• Focuses on heart failure-specific keywords like “ARNi”, “mortality reduction”, “hospitalization prevention”.

• Emphasizes Bangladesh-specific pricing and local manufacturer (Square Pharmaceuticals) to boost relevance.

• Includes safety, dosage, and interaction keywords that align with common search intents and increase credibility.