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Valoate CR 300 mg Tablet

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8.00 Tk

✅ Product Benefits

  1. Extended‑release formula
    Sustained delivery reduces peaks and troughs, minimizing nausea and GI upset common with immediate-release forms. 

  2. Broad-spectrum clinical use
    Module for various seizure types (e.g. tonic‑clonic, absence, myoclonic), bipolar mania, febrile convulsions, and migraine prophylaxis. 

  3. Flexible dosing regimens
    Can be given once or twice daily. Adult titration starts around 600 mg/day (in divided doses), increased to 1–2 g/day based on clinical goals. Pediatric dosing weight-based. 

  4. GABA potentiator
    Increases brain GABA levels, helping stabilize neuronal excitability and mood regulation.

  5. Well‑documented safety monitoring framework
    Requires liver function monitoring due to risk of hepatic enzyme rise; rare cases of fatal hepatitis especially under age 2 or with polytherapy. 

    Common and rare side effects

  6. Frequent: nausea, vomiting, sedation, tremor, weight gain, hair loss. Rare: pancreatitis, thrombo‑cytopenia, cognitive effects, Stevens-Johnson syndrome. 

  7. Minimal drug metabolism interactions
    Inhibits CYP2C9 and phase II pathways; interacts with phenobarbital, phenytoin, warfarin, and aspirin. 

  8. Contraindications
    Not recommended in liver dysfunction, urea cycle disorders, known hypersensitivity, or during pregnancy (high teratogenic risk).

  9. Affordable & widely available
    Priced at about ৳0.80 per tablet (~৳8 per strip of 10); distributed through major Bangladeshi pharmacies.

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