✅ Product Benefits
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Controlled-release delivery Each enteric-coated
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Broad-spectrum seizure control
Indicated for all seizure types—including partial, absence, generalized tonic-clonic, myoclonic, atonic, and mixed seizures—plus febrile convulsion and post-traumatic epilepsy prophylaxis. Also used in bipolar disorder and migraine prevention. -
Flexible dosing protocol
Adults usually start at 600 mg/day in 2 divided doses (after meals), incrementally increased by 200 mg every 3 days up to 2.5 g/day until seizure control achieved. Maintenance range 1–2 g/day (20–30 mg/kg). Occasional pediatric guidance available based on weight. -
Well-established mechanism & efficacy
Thought to elevate brain GABA levels and stabilize neuronal activity, thereby preventing seizures and mood fluctuations. -
Safety profile & side effect management
Common side effects include nausea, anorexia, drowsiness, tremor, and weight gain. Liver enzyme elevation occurs in ~40% of patients—typically early in therapy. Rare but serious risks include fulminant hepatitis, pancreatitis, thrombocytopenia, and hyperammonemia. Regular liver and blood monitoring recommended. -
Drug interactions and precautions
As a non-specific inhibitor of drug metabolism, interacts notably with phenobarbital, phenytoin, warfarin, aspirin, and others. Contraindicated in liver dysfunction, urea cycle disorders, porphyria, and during pregnancy due to high risk of neural tube defects (e.g., spina bifida) and developmental impairment. Should be avoided or carefully managed in women of childbearing potential. -
Affordability & availability in Bangladesh
Unit price approximately ৳12.03 per tablet (~৳120 per strip of 10). Manufactured locally by Square Pharmaceuticals, and distributed widely across pharmacies and e-commerce platforms.
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